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Publications

Seminal publication describing the discovery and development of Togni-CF2CF2R reagents

Matoušek V., Václavík J., Hájek P., Charpentier J., Blastik Z.E., Pietrasiak E., Budinská A., Togni A., Beier P.:

Expanding the Scope of Hypervalent Iodine Reagents for Perfluoroalkylation: From Trifluoromethyl to Functionalized Perfluoroethyl.

Chemistry - A European Journal 22: 417-424, 2016

Publication describing the development an amine platform Togni reagent, its late-stage functionalisation and the application of the complex Togni reagents to chemoselective thiol bioconjugation

Václavík J., Zschoche R., Klimánková I., Matoušek V., Beier P., Hilvert D., Togni A.:

Irreversible Cysteine-Selective Protein Labeling Employing Modular Electrophilic Tetrafluoroethylation Reagents.

Chemistry – A European Journal 23: 6490-6494, 2017

Publication describing the magnesiation of fluoroalkylbromides of the formula RCF2CF2Br and their application in synthesis of tetrafluoroethylated small molecules

Budinská A., Václavík J., Matoušek V., Beier P.:

Nucleophilic Tetrafluoroethylation Employing in Situ Formed Organomagnesium Reagents.

Organic Letters 18: 5844-5847, 2016

Publication describing the synthesis of perfluoroalkylazides from nucleophilic perfluoroalkyl sources and their application in copper-catalyzed azide-alkyne cycloaddition (CuAAC)

Blastik Z.E., Voltrová S., Matoušek V., Jurásek B., Manley D., Klepetářová B., Beier P.:

Azidoperfluoroalkanes: Synthesis and Application in Copper(I)-Catalyzed Azide-Alkyne Cycloaddition.

Angewandte Chemie International Edition 56: 346-349, 2017

Publication describing the synthesis of tetrafluoroalkyl azides of the formula RCF2CF2N3 and their application in copper-catalyzed azide-alkyne cycloaddition (CuAAC)

Voltrová S., Muselli M., Filgas J., Matoušek V., Klepetářová B., Beier P.:

Synthesis of tetrafluoroethylene- and tetrafluoroethyl-containing azides and their 1,3-dipolar cycloaddition as synthetic application.

Organic and Biomolecular Chemistry 15: 4962-4965, 2017

Publication describing the access to difluoromethyl azide and its application in copper-catalyzed azide-alkyne cycloaddition (CuAAC)

manuscript accepted