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Phenoxytetrafluoroethanesulfonyl fluoride

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SF006_0250 0,25 g in stock login to see the price
SF006_0500 0,5 g in stock login to see the price
SF006_1 1 g in stock login to see the price
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  • IUPAC Name: 1,1,2,2-tetrafluoro-2-phenoxyethane-1-sulfonyl fluoride
  • Synonyms: PhOCF2CF2SO2F, Phenoxytetrafluoroethanesulphonyl fluoride
  • CAS: N/A
  • Smiles: FC(F)(C(F)(S(=O)(F)=O)F)OC1=CC=CC=C1
  • Chemical formula: C8H5F5O3S
  • Molecular weight: 276,179
  • Purity: 95%+

Phenoxytetrafluoroethanesulfonyl fluoride serves as a moderately reactive phenoxytetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of NH and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen.