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N-Difluoromethyltributylammonium chloride

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  • IUPAC Name: N-Difluoromethyltributylammonium chloride
  • Synonyms: HCF2NBu3Cl, Difluoromethyl tributylammonium chloride, Tributyl difluoromethylammonium chloride
  • CAS: 1004517-48-9
  • Smiles: CCCC[N+](CCCC)(C(F)F)CCCC.[Cl-]
  • Chemical formula: C13H28ClF2N
  • Molecular weight: 271.82
  • Purity: 95%+

N-Difluoromethyltributylammonium chloride is an effective source of difluorocarbene for

difluoromethylation of O-,S-,N-,C- centred nucleophiles under mild conditions. Using only

1.2 equivalent of this reagent, difluoromethylated products can be obtained in moderate to excellent

yields under mild conditions.