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Di-(N-succinimidyl) suberate

Cat. # Quantity Price Lead time Buy this product
PCL002_1 1 g 50,00 € in stock
PCL002_5 5 g 190,00 € in stock
PCL002_10 10 g 300,00 € in stock
PCL002_50 50 g 1.350,00 € in stock
  • IUPAC Name: 1-(2,5-Dioxocyclopentyl) 8-(2,5-dioxopyrrolidin-1-yl) octanedioate
  • Synonyms: DSS, Disuccinimidyl suberate, Disuccinimidyl octanedioate
  • CAS: 68528-80-3
  • Smiles: O=C(ON1C(CCC1=O)=O)CCCCCCC(OC2C(CCC2=O)=O)=O
  • Chemical formula: C16H20N2O8
  • Molecular weight: 368.34
  • Purity: 98%+

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

Application
Suberic acid bis(N-hydroxysuccinimide ester) has been:
• supplemented in pierce lysis buffer used for immunoprecipitation
• used to conjugate the oligonucleotide standards to gelatin
• used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers