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Di-(N-succinimidyl) pimelate

Cat. # Quantity Price Lead time Buy this product
PCL009_1 1 g 120,00 € in stock
PCL009_5 5 g 400,00 € in stock
PCL009_10 10 g 640,00 € in stock
PCL009_50 50 g 2.490,00 € in stock
  • IUPAC Name: Bis(2,5-dioxopyrrolidin-1-yl) heptanedioate
  • Synonyms: Disuccinimidyl pimelate, Disuccinimidyl heptanedioate, Di(N-succinimidyl) pimelate, Bis(2,5-dioxopyrrolidin-1-yl) pimelate
  • CAS: 74648-14-9
  • Smiles: O=C(CCC1=O)N1OC(CCCCCC(ON2C(CCC2=O)=O)=O)=O
  • Chemical formula: C15H18N2O8
  • Molecular weight: 354.31
  • Purity: 98%+

Di-(N-succinimidyl) pimelate is an amine-reactive homobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups and N-termini. While generally less often used than DSG, DSS and DSSeb, protein structure analysis based on chemical crosslinking with disuccinimidyl pimelate can generate additional structural information.