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Di-(N-Succinimidyl) Pimelate

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PCL009_1 1 g in stock login to see the price
PCL009_5 5 g in stock login to see the price
  • IUPAC Name: bis(2,5-dioxopyrrolidin-1-yl) heptanedioate
  • Synonyms: disuccinimidyl pimelate; disuccinimidyl heptanedioate; Di-(N-Succinimidyl) Pimelate; bis(2,5-dioxopyrrolidin-1-yl) pimelate
  • CAS: 74648-14-9
  • Smiles: O=C(CCC1=O)N1OC(CCCCCC(ON2C(CCC2=O)=O)=O)=O
  • Chemical formula: C15H18N2O8
  • Molecular weight: 354,31
  • Purity: 98%+

Di-(N-Succinimidyl) Pimelate is an amine-reactive homobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups and N-termini. While generally less often used than DSG, DSS and DSSeb, protein structure analysis based on chemical crosslinking with disuccinimidyl pimelate can generate additional structural information.