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Di-(N-Succinimidyl) Adipate

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PCL005_1 1 g in stock login to see the price
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  • IUPAC Name: bis(2,5-dioxopyrrolidin-1-yl) adipate
  • Synonyms: DSA; Disuccinimidyl adipate;disuccinimidyl hexanedioate; Di-(N-Succinimidyl) Adipate
  • CAS: 59156-70-6
  • Smiles: O=C(ON1C(CCC1=O)=O)CCCCC(ON2C(CCC2=O)=O)=O
  • Chemical formula: C14H16N2O8
  • Molecular weight: 340,29
  • Purity: 98%+

Di-(N-Succinimidyl) Adipate is an amine-reactive homobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups and N-termini. While generally less often used than DSG, DSS and DSSeb, protein structure analysis based on chemical crosslinking with DSA can generate additional structural information.