|Cat. #||Quantity||Lead time||Buy this product|
|PCL011_1||1 g||in stock||login to see the price|
|PCL011_5||5 g||in stock||login to see the price|
|PCL011_10||10 g||in stock||login to see the price|
Di-(N-succinimidyl) 3,3-dithiodipropionate is an amine-reactive homobifunctional cross-linker with a cleavable disulfide moiety. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups and N-termini. The resulting crosslinks can be effectively cleaved under reductive conditions, for example by treatment with DTT or TCEP.