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Benzimidazolyltetrafluoroethanesulfonyl fluoride

Cat. # Quantity Price Lead time Buy this product
SF007_0250 0.25 g 450,00 € in stock
SF007_0500 0.5 g 700,00 € in stock
SF007_1 1 g 1.200,00 € in stock
SF007_5 5 g 3.990,00 € in stock
  • IUPAC Name: 2-(1H-Benzo[d]imidazol-1-yl)-1,1,2,2-tetrafluoroethane-1-sulfonyl fluoride
  • Synonyms: BenzimCF2CF2SO2F, Benzimidazolyltetrafluoroethanesulphonyl fluoride
  • CAS: N/A
  • Smiles: FC(F)(C(F)(S(=O)(F)=O)F)N1C(C=CC=C2)=C2N=C1
  • Chemical formula: C9H5F5O2N2
  • Molecular weight: 300.204
  • Purity: 95%+

Benzimidazolyltetrafluoroethanesulfonyl fluoride serves as a moderately reactive benzimidazolyltetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of NH and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen.