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Acid CF3-reagent (Togni Reagent II)

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HYP001_1 1 g in stock login to see the price
HYP001_5 5 g in stock login to see the price
HYP001_10 10 g in stock login to see the price
HYP001_100 100 g in stock login to see the price
HYP001_1000 1000 g in stock login to see the price
  • IUPAC Name: 1-(Trifluoromethyl)-1λ3-benzo[d][1,2]iodaoxol-3(1H)-one
  • Synonyms: Togni reagent II; Acid-CF3 Togni reagent
  • CAS: 887144-94-7
  • Smiles: O=C(OI1C(F)(F)F)C2=C1C=CC=C2
  • Chemical formula: C8H4F3IO2
  • Molecular weight: 316,02
  • Purity: 95 %

Acid CF*3*-reagent (or termed as Togni Reagent II) is the second commercialized hypervalent iodine CF*3*-reagent. Its main difference from Alcohol-CF*3*-reagent is higher crystallinity and lower solubility in organic solvents at comparable conditions. Generally speaking, polar solvents are preferred for reactions where Acid-CF*3*-reagent is used (typically THF, DCM, MeCN, alcohols, glymes).