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6-Azidohexanoic acid NHS ester

Cat. # Quantity Lead time Buy this product
PCL021_0250 0.25 g in stock login to see the price
PCL021_0500 0.5 g in stock login to see the price
PCL021_1 1 g in stock login to see the price
PCL021_5 5 g in stock login to see the price
  • IUPAC Name: 2,5-Dioxopyrrolidin-1-yl 6-azidohexanoate
  • Synonyms: 6-Azidohexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester, 6-Azidohexanoic acid N-hydroxysuccinimide ester, 1-[(6-Azidohexanoyl)oxy]pyrrolidine-2,5-dione, 6-Azidohexanoic N-hydroxysuccinimide ester, 2,5-Dioxopyrrolidin-1-yl-6-azidohexanoate
  • CAS: 866363-70-4
  • Smiles: O=C(CCCCCN=[N+]=[N-])ON1C(CCC1=O)=O
  • Chemical formula: C10H14N4O4
  • Molecular weight: 254.246
  • Purity: 95%+

4-Azidohexanoic acid NHS ester is an amine-reactive heterobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups, N-termini and amines and installs the alkylazido group that serves as a bioorthogonal handle for copper-catalyzed alkyne-azide cycloaddition (CuAAC).