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4-Chlorophenoxytetrafluoroethanesulfonyl fluoride

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SF003_0250 0.25 g in stock login to see the price
SF003_0500 0.5 g in stock login to see the price
SF003_1 1 g in stock login to see the price
SF003_5 5 g in stock login to see the price
  • IUPAC Name: 2-(4-Chlorophenoxy)-1,1,2,2-tetrafluoroethane-1-sulfonyl fluoride
  • Synonyms: 4-ClPhOCF2CF2SO2F, 4-Chlorophenoxytetrafluoroethanesulphonyl fluoride
  • CAS: N/A
  • Smiles: FC(F)(C(F)(S(=O)(F)=O)F)OC1=CC=C(Cl)C=C1
  • Chemical formula: C8H4F5O3S
  • Molecular weight: 310.625
  • Purity: 95%+

4-Chlorophenoxytetrafluoroethanesulfonyl fluoride serves as a moderately reactive 4-chlorophenoxytetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of NH and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen. Regioisomers are also available on demand.