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4-Bromophenoxytetrafluoroethanesulfonyl fluoride

Cat. # Quantity Lead time Buy this product
SF002_0250 0.25 g in stock login to see the price
SF002_0500 0.5 g in stock login to see the price
SF002_1 1 g in stock login to see the price
SF002_5 5 g in stock login to see the price
  • IUPAC Name: 2-(4-Bromophenoxy)-1,1,2,2-tetrafluoroethane-1-sulfonyl fluoride
  • Synonyms: 4-BrPhOCF2CF2SO2F, 4-Bromophenoxytetrafluoroethanesulphonyl fluoride
  • CAS: 252975-60-3
  • Smiles: FC(F)(C(F)(S(=O)(F)=O)F)OC1=CC=C(Br)C=C1
  • Chemical formula: C8H4BrF5O3S
  • Molecular weight: 355.076
  • Purity: 95%+

4-Bromophenoxytetrafluoroethanesulfonyl fluoride serves as a moderately reactive 4-bromophenoxytetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of NH and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen. Regioisomers are also available on demand.