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4-Azidobutyric acid NHS ester

Cat. # Quantity Lead time Buy this product
PCL015_0250 0.25 g in stock login to see the price
PCL015_0500 0.5 g in stock login to see the price
PCL015_1 1 g in stock login to see the price
PCL015_5 5 g in stock login to see the price
  • IUPAC Name: 2,5-Dioxopyrrolidin-1-yl 4-azidobutanoate
  • Synonyms: Azidobutyric NHS ester, NHS Azidobutyrate
  • CAS: 943858-70-6
  • Smiles: O=C(ON1C(CCC1=O)=O)CCCN=[N+]=[N-]
  • Chemical formula: C8H10N4O4
  • Molecular weight: 226.19
  • Purity: 95%+

4-Azidobutyric acid NHS ester is an amine-reactive heterobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups, N-termini and amines and installs the alkylazido group that serves as a bioorthogonal handle for copper-catalyzed alkyne-azide cycloaddition (CuAAC).