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2-Azidoacetic NHS ester

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PCL022_1 1 g in stock login to see the price
PCL022_5 5 g in stock login to see the price
PCL022_10 10 g in stock login to see the price
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  • IUPAC Name: 2,5-Dioxopyrrolidin-1-yl 2-azidoacetate
  • Synonyms: Succinimidyl 2-azidoacetate, Succinimidyl azidoacetate, 2-Azidoacetic succinimidyl ester, Azidoacetic succinimidyl ester
  • CAS: 824426-32-6
  • Smiles: O=C(CN=[N+]=[N-])ON1C(CCC1=O)=O
  • Chemical formula: C6H6N4O4
  • Molecular weight: 198.14
  • Purity: 95%+

2-Azidoacetic acid NHS ester is an amine-reactive heterobifunctional cross-linker. At neutral or slightly basic pH (7-9), it rapidly attacks solvent accessible lysine-NH2 groups, N-termini and amines and installs the alkylazido group that serves as a bioorthogonal handle for copper-catalyzed alkyne-azide cycloaddition (CuAAC).